Testosterone Deficiency Syndrome

Testosterone deficiency syndrome is a clinical condition characterized by lower than normal levels of testosterone in a man’s blood. It is also known as “andropause”, “late-onset hypogonadism” or “low testosterone”. It is characterized by decreased testosterone synthesis in testicles and can cause major health issues by affecting multiple organ systems. The incidence rate is 6% in middle-aged men. It may be more prevalent in elder and obese men.

What is the function of testosterone?

Testosterone is a major hormone involved in many functions. It does not only play a role in maintaining sexual desire and erectile functionality, but also is important for vital functions such as the reduction of fat and improvement of muscle mass, protection of bone mineral density, and maintaining cardiovascular health, blood production and cognitive functions.

What are the symptoms of hypogonadism in men?

• Lack of sexual desire
• Erectile dysfunction
• Irritability, nervousness
• Depression
• Decreased bone density and muscle mass
• Arthralgia and myalgia
• Excessive sweating, flushing
• Increased fat mass and obesity
• Decline in cognitive functions
• Insomnia

How is hypogonadism treated?

Testosterone replacement is the most frequently preferred treatment in hypogonadism. The goal is to elevate testosterone levels in order to restore sexual desire and erectile function, increase muscle strength, decrease fat mass, improve bone density, enhance cognitive functions and improve physical performance and quality of life.